CD130/gp130 anticorps (pSer782) (AbBy Fluor® 350)
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- Antigène Voir toutes CD130/gp130 (IL6ST) Anticorps
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
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Épitope
- pSer782
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CD130/gp130 est conjugé à/à la AbBy Fluor® 350
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Humain, Rat
- Homologie
- Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human gp130 around the phosphorylation site of Ser782
- Isotype
- IgG
- Top Product
- Discover our top product IL6ST Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- Autre désignation
- gp130 (IL6ST Produits)
- Synonymes
- anticorps CD130, anticorps CDW130, anticorps GP130, anticorps IL-6RB, anticorps 5133400A03Rik, anticorps AA389424, anticorps BB405851, anticorps D13Ertd699e, anticorps gp130, anticorps Ac1055, anticorps Gp130, anticorps Il-6rb, anticorps IL-6, anticorps interleukin 6 signal transducer, anticorps IL6ST, anticorps Il6st, anticorps il6st
- Sujet
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Synonyms: gp130 phospho S782, gp130 phospho Ser782, p-gp130 Ser782, Interleukin-6 receptor subunit beta, IL-6R-beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, gp130, CDw130, Oncostatin-M receptor subunit alpha, CD_antigen, CD130, GP130 RAPS, gp130 transducer chain, GP130-RAPS, IL6 ST, IL6R-beta, IL6ST.IL6R-beta, IL6RB_HUMAN, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB.
Background: CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
- ID gène
- 3572
- UniProt
- P40189
- Pathways
- Signalistation JAK/STAT, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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