Cofilin 1 (Non-Muscle) (CFL1) (pSer24) anticorps (Cy5)

Détails pour le produit réf. ABIN1704204
Antigène
  • cfl1
  • xac1
  • xac2
  • cfl
  • cb86
  • sb:cb86
  • zgc:56501
  • wu:fb18a04
  • wu:fk77b03
  • 12/8
  • ADF
  • ADF/cofilin
  • Adf
  • CG4254
  • Cadf
  • D-cof
  • D61
  • Dmel\\CG4254
  • T8
  • Tsr
  • cofilin
  • cofilin/ADF
  • cofilin/actin depolymerizing factor homolog
  • l(2)03101
  • l(2)k03101
  • l(2)k05633
  • l(2)k13409
  • ntf
  • CFL
  • AA959946
  • Cof
  • CFL1
  • cofilin 1 (non-muscle) L homeolog
  • cofilin 1 (non-muscle)
  • cofilin 1 (non-muscle), like
  • cofilin 1
  • twinstar
  • cofilin
  • cofilin 1, non-muscle
  • Contrafreeloading
  • cfl1.L
  • cfl1
  • cfl1l
  • CFL1
  • tsr
  • COF1
  • TSTA_042790
  • Cfl1
  • CFL
Épitope
pSer24
63
30
22
20
19
14
12
9
9
8
7
5
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
331
205
173
11
11
9
7
2
2
2
2
1
Hôte
Lapin
297
34
3
Clonalité
Polyclonal
Conjugué
Cy5
15
11
9
7
7
6
6
6
6
6
6
5
2
2
2
2
2
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
225
135
134
49
48
27
25
17
15
13
10
4
4
3
2
Options
Immunogène KLH conjugated synthetic phosphopeptide derived from human CFL1/CFL2 around the phosphorylation site of Ser24
Isotype IgG
Purification Purified by Protein A.
Antigène
Autre désignation Cofilin (CFL1 Antibody Extrait)
Sujet

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Synonyms: Cofilin/CFL1 Ser24, 18 kDa phosphoprotein, CFL 1, CFL, CFL1, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, p18, COF1_HUMAN.

ID gène 1072
Pathways Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
Indications d'application IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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