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GMEB1 anticorps (AA 301-400) (HRP)

GMEB1 Reactivité: Humain WB, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1711895
  • Antigène Voir toutes GMEB1 Anticorps
    GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
    Épitope
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reactivité
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 24
    • 2
    Lapin
    Clonalité
    • 24
    • 2
    Polyclonal
    Conjugué
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GMEB1 est conjugé à/à la HRP
    Application
    • 13
    • 13
    • 9
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GMEB1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
    Autre désignation
    GMEB1 (GMEB1 Produits)
    Synonymes
    anticorps MGC81052, anticorps GMEB1, anticorps si:ch211-245h7.5, anticorps pif96, anticorps p96pif, anticorps MGC147529, anticorps P96PIF, anticorps PIF96, anticorps 1110050A04Rik, anticorps AI256615, anticorps AI481278, anticorps RGD1563208, anticorps glucocorticoid modulatory element binding protein 1 S homeolog, anticorps glucocorticoid modulatory element binding protein 1, anticorps gmeb1.S, anticorps GMEB1, anticorps gmeb1, anticorps Gmeb1
    Sujet

    GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: DNA binding protein p96P, DNA-binding protein p96P, Glucocorticoid modulatory element binding protein 1, Glucocorticoid modulatory element-binding protein 1, GMEB 1, GMEB-1, Gmeb1, GMEB1_HUMAN, P96P, Parvovirus initiation factor p96, P 96, P p96, P96.

    ID gène
    10691
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