GMEB1 anticorps (AA 301-400)
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- Antigène Voir toutes GMEB1 Anticorps
- GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
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Épitope
- AA 301-400
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GMEB1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GMEB1
- Isotype
- IgG
- Top Product
- Discover our top product GMEB1 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
- Autre désignation
- GMEB1 (GMEB1 Produits)
- Synonymes
- anticorps MGC81052, anticorps GMEB1, anticorps si:ch211-245h7.5, anticorps pif96, anticorps p96pif, anticorps MGC147529, anticorps P96PIF, anticorps PIF96, anticorps 1110050A04Rik, anticorps AI256615, anticorps AI481278, anticorps RGD1563208, anticorps glucocorticoid modulatory element binding protein 1 S homeolog, anticorps glucocorticoid modulatory element binding protein 1, anticorps gmeb1.S, anticorps GMEB1, anticorps gmeb1, anticorps Gmeb1
- Sujet
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Synonyms: DNA binding protein p96P, DNA-binding protein p96P, Glucocorticoid modulatory element binding protein 1, Glucocorticoid modulatory element-binding protein 1, GMEB 1, GMEB-1, Gmeb1, GMEB1_HUMAN, P96P, Parvovirus initiation factor p96, P 96, P p96, P96.
Background: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.
- ID gène
- 10691
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