SH3KBP1 anticorps (AA 201-300)

N° du produit ABIN1713895

Détail du produit anti-SH3KBP1 anticorps

Antigène: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Épitope: AA 201-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3KBP1 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SH3KBP1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SH3KBP1

Antigène: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Autre désignation: SH3KBP1 (SH3KBP1 Produits)

Synonymes: anticorps CD2BP3, anticorps CIN85, anticorps GIG10, anticorps HSB-1, anticorps HSB1, anticorps MIG18, anticorps 1200007H22Rik, anticorps 1700125L08Rik, anticorps 5830464D22Rik, anticorps AI447724, anticorps IN85, anticorps Ruk, anticorps Seta, anticorps SH3 domain containing kinase binding protein 1, anticorps SH3-domain kinase binding protein 1, anticorps SH3 domain-containing kinase-binding protein 1, anticorps SH3KBP1, anticorps sh3kbp1, anticorps LOC100551401, anticorps Sh3kbp1

Sujet:

Synonyms: c Cbl interacting protein, Cbl interacting protein, Cbl interacting protein of 85 kDa, Cbl-interacting protein of 85 kDa, CD2 binding protein 3, CD2-binding protein 3, CD2BP3, CIN 85, CIN85, GIG 10, GIG10, HSB 1, HSB-1, HSB1, Human Src family kinase binding protein 1, Human Src family kinase-binding protein 1, MIG 18, MIG18, Migration inducing gene 18, Migration inducing gene 18 protein, SH3 domain kinase binding protein 1, SH3 domain-containing kinase-binding protein 1, SH3BP 1, SH3K1_HUMAN, SH3KBP1, Src family kinase binding protein 1, src related kinase binding protein 1.

Background: SHKBP1 is a 707 amino acid protein belonging to the KCTD3 family. Acting downstream of Flt-3/Flk-2, SHKBP1 interacts with CIN85. SHKBP1 contains a BTB/POZ domain, which is involved in ring canal formation and chromatin folding, and five WB repeats. SHKBP1 exists as two alternatively spliced isoforms and maps to human chromosome 19q13.2. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Pathways: EGFR Signaling Pathway, EGFR Downregulation