CLEC7A anticorps (Biotin)
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- Antigène Voir toutes CLEC7A Anticorps
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CLEC7A est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Recognizes murine beta-glucan receptor, also known as Dectin-1. Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macrophages via the protein tyrosine kinase known as Syk. Inhibits the binding of zymosan to macrophages via the beta-glucan receptor. The low endotoxin version is recommended for functional studies.
- Purification
- Protein G purified
- Immunogène
- Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1.
- Clone
- 2A11
- Isotype
- IgG2b
- Top Product
- Discover our top product CLEC7A Anticorps primaire
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- Indications d'application
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Approved: Flo (1:1 - 1:10), IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Commentaires
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Target Species of Antibody: Mouse
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide, 1 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing. Protect from light.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
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- Antigène
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Autre désignation
- CLEC7A / Dectin 1 (CLEC7A Produits)
- Synonymes
- anticorps CLEC7A, anticorps BGR, anticorps Clecsf12, anticorps beta-GR, anticorps CANDF4, anticorps CLECSF12, anticorps DECTIN1, anticorps Clec7b, anticorps RGD1565140, anticorps C-type lectin domain containing 7A, anticorps C-type lectin domain family 7, member a, anticorps CLEC7A, anticorps Clec7a
- Sujet
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Name/Gene ID: CLEC7A
Synonyms: CLEC7A, BGR, CANDF4, CLECSF12, Dectin-1, DC-associated C-type lectin 1, DECTIN1, HDectin-1, Beta-glucan receptor, Lectin-like receptor 1 - ID gène
- 64581
- Pathways
- Activation of Innate immune Response
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