Interferon gamma anticorps

N° du produit ABIN1844061

Détail du produit anti-Interferon gamma anticorps

Antigène: Interferon gamma (IFNG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Interferon gamma est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human IFN-gamma expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Détails sur Interferon gamma

Antigène: Interferon gamma (IFNG)

Autre désignation: IFN gamma (IFNG Produits)

Synonymes: anticorps IFG, anticorps IFI, anticorps IFN-g, anticorps Ifg, anticorps IFNG2, anticorps IFN-gamma, anticorps IFN-G, anticorps IFNG, anticorps IFNgamma, anticorps TCRalpha, anticorps INF-G, anticorps ifng, anticorps interferon gamma, anticorps interferon, gamma 1-2, anticorps IFNG, anticorps Ifng, anticorps ifng1-2

Sujet: Interferon gamma (IFN gamma ) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon gamma through the activation of transcription factor NFKB.

Poids moléculaire: 19 kDa

ID gène: 3458

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy