IRS1 anticorps (pSer307)

N° du produit ABIN1844090

Détail du produit anti-IRS1 anticorps

Antigène: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Épitope: pSer307

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Specificité: Phospho-IRS-1 (Ser307) Antibody detects endogenous levels of IRS-1 only when phosphorylated at Serine 307.

Purification: Immunogen affinity purified

Immunogène: A synthesized peptide derived from human IRS-1 around the phosphorylation site of Serine307.

Information d'application

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stockage commentaire: Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur IRS1

Antigène: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Autre désignation: IRS-1 (IRS1 Produits)

Synonymes: anticorps HIRS-1, anticorps G972R, anticorps IRS-1, anticorps IRS1IRM, anticorps irs1, anticorps irsu, anticorps IRS1, anticorps irs-1, anticorps irs1-a, anticorps insulin receptor substrate 1, anticorps insulin receptor substrate 2, anticorps insulin receptor substrate 1 S homeolog, anticorps IRS1, anticorps Irs1, anticorps irs2, anticorps irs1.S

Sujet: IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2.

Poids moléculaire: 180 kDa

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process