Cyclin D3 anticorps

N° du produit ABIN1845423

Détail du produit anti-Cyclin D3 anticorps

Antigène: Cyclin D3 (CCND3)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin D3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Ascitic fluid containing 0.03% sodium azide.

Immunogène: Purified recombinant fragment of human CCND3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C.

Détails sur Cyclin D3

Antigène: Cyclin D3 (CCND3)

Autre désignation: CCND3 (CCND3 Produits)

Synonymes: anticorps zgc:103502, anticorps CCND3, anticorps 9230106B05Rik, anticorps AA682053, anticorps AL024085, anticorps AW146355, anticorps C78795, anticorps cyclin D3, anticorps ccnd3, anticorps CCND3, anticorps Ccnd3

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 32 kDa

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process