FAS anticorps (FITC)

N° du produit ABIN187286

Détail du produit anti-FAS anticorps (FITC)

Antigène: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FAS est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: Species Reactivity: Human. Others not tested.

Clone: 3-22

Isotype: IgG1

Information d'application

Indications d'application: Monitoring of activated T cells in peripheral blood, Analysis of NK subsets, Study of B cell activation. Flow cytometry Immunofluorescence PBMC: Add 10 µL of mAb/106 PBMC in 100 µL PBS. Mix gently and incubate for 15 minutes at 4 °C. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. Whole Blood: Add 10 µL of mAb/100 µL of whole blood. Mix gently and incubate for 15 minutes at room temperature (RT). Lyse the whole blood. Wash once with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. See instrument manufacturer's instructions for lysed whole blood and immunofluorescence analysis with a flow cytometer or microscope. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 1.0 mL of FITC-labeled monoclonal antibody in PBS, 0.08% sodium azide and protein stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur FAS

Antigène: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Autre désignation: CD95 / FAS (FAS Produits)

Synonymes: anticorps ALPS1A, anticorps APO-1, anticorps APT1, anticorps CD95, anticorps FAS1, anticorps FASTM, anticorps TNFRSF6, anticorps AI196731, anticorps APO1, anticorps TNFR6, anticorps Tnfrsf6, anticorps lpr, anticorps Fas cell surface death receptor, anticorps Fas (TNF receptor superfamily member 6), anticorps FAS, anticorps Fas, anticorps fas

Sujet: Activation of either the 55 kDa tumor necrosis factor receptor (TNF-R1) or CD95 (Fas/Apo-1) causes apoptosis of cells and liver failure in mice, and has been associated with human liver disorders.

Pathways: Signalisation p53, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity