NME1 anticorps

N° du produit ABIN1882270

Détail du produit anti-NME1 anticorps

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NME1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: Purified His-tagged NME1 protein was used to produced this monoclonal antibody.

Clone: 1172CT2-4-1-1

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-NME1 (ABIN1882270)

Garcia-Esparcia, Hernández-Ortega, Ansoleaga, Carmona, Ferrer: "Purine metabolism gene deregulation in Parkinson's disease." dans: Neuropathology and applied neurobiology, (2015) (PubMed).

Ni, Gu, Dai, Cheng, Guo, Li, Ji, Xie, Ying, Mao: "Isolation and characterization of a novel human NM23-H1B gene, a different transcript of NM23-H1." dans: Journal of human genetics, Vol. 48, Issue 2, pp. 96-100, (2003) (PubMed).

Dooley, Seib, Engel, Theisinger, Janz, Piontek, Zang, Welter: "Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1." dans: Human genetics, Vol. 93, Issue 1, pp. 63-6, (1994) (PubMed).

Gilles, Presecan, Vonica, Lascu: "Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme." dans: The Journal of biological chemistry, Vol. 266, Issue 14, pp. 8784-9, (1991) (PubMed).

Rosengard, Krutzsch, Shearn, Biggs, Barker, Margulies, King, Liotta, Steeg: "Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development." dans: Nature, Vol. 342, Issue 6246, pp. 177-80, (1989) (PubMed).

Détails sur NME1

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Autre désignation: NME1 (NME1 Produits)

Synonymes: anticorps AWD, anticorps GAAD, anticorps NB, anticorps NBS, anticorps NDKA, anticorps NDPK-A, anticorps NDPKA, anticorps NM23, anticorps NM23-H1, anticorps AL024257, anticorps NM23-M1, anticorps NM23A, anticorps NDPK-Z1, anticorps NM23-B, anticorps NM23-Z1, anticorps ndpkz1, anticorps nm23b, anticorps nme1, anticorps nme2, anticorps nme2b1, anticorps NME1, anticorps NME1-NME2, anticorps NM23-C1, anticorps ndpk-b, anticorps ndpkb, anticorps nm23-h2, anticorps nm23ndk, anticorps puf, anticorps NBR-A, anticorps NBR-B, anticorps NME1-1, anticorps nm23ndk-a, anticorps NDK I, anticorps NDPK I, anticorps T30A10.80, anticorps T30A10_80, anticorps NDP kinase I, anticorps NME/NM23 nucleoside diphosphate kinase 1, anticorps NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1, anticorps non-metastatic cells 1, protein (NM23A) expressed in, anticorps NME/NM23 nucleoside diphosphate kinase 2 S homeolog, anticorps NME/NM23 nucleoside diphosphate kinase 2 L homeolog, anticorps nucleoside diphosphate kinase, anticorps nucleoside diphosphate kinase 1, anticorps NME1, anticorps Nme1, anticorps nme2b.1, anticorps nme2.S, anticorps nme2.L, anticorps LOC547870, anticorps NDPK1, anticorps LOC107790563

Sujet: Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.

Poids moléculaire: 17149

NCBI Accession: NP_000260, NP_937818

UniProt: P15531

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process