PRKACA
Reactivité: Humain
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
Biohazard Informations: This product contains thimerosal which is hazardous.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Antigène
PRKACA
(Protein Kinase A, alpha (PRKACA))
Autre désignation
PRKACA
Sujet
CAMP is a signaling molecule important for a variety of cellular functions.cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins.The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits.cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.Four different regulatory subunits and three catalytic subunits have been identified in humans.The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.Alternatively spliced transcript variants encoding distinct isoforms have been observed.[provided by RefSeq]