IL21R
Reactivité: Humain
FACS
Hôte: Souris
Monoclonal
17A12
PE
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
A novel cytokine related to IL2 and IL15 was recently identified and designated IL-21.The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family.IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling.Both IL-21R and the gc are necessary for the IL-21 function.IL-21 and its receptor activate JAK-STAT signaling pathway.IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines.IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations. Synonyms: IL21R