MANF anticorps (C-Term)

N° du produit ABIN1886911

Détail du produit anti-MANF anticorps

Antigène: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MANF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): This antibody does not cross-react with CDNF.

Purification: Affinity chromatography purified via peptide column

Immunogène: 12 amino acid peptide from near the carboxy terminus of human MANF.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur MANF

Antigène: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Autre désignation: MANF (MANF Produits)

Synonymes: anticorps ARMET, anticorps ARP, anticorps 3230402M22Rik, anticorps AA407711, anticorps AA408789, anticorps AA673178, anticorps Armet, anticorps D17914, anticorps D18Mgi17, anticorps MANF, anticorps RBM15B, anticorps ARP-like, anticorps CG7013, anticorps DmMANF, anticorps Dmel\\CG7013, anticorps anon-EST:ParkEST188, anticorps arp, anticorps armet, anticorps im:6909481, anticorps zgc:153327, anticorps manf, anticorps mesencephalic astrocyte derived neurotrophic factor, anticorps mesencephalic astrocyte-derived neurotrophic factor, anticorps RNA binding motif protein 15B, anticorps Mesencephalic astrocyte-derived neurotrophic factor, anticorps mesencephalic astrocyte-derived neurotrophic factor S homeolog, anticorps MANF, anticorps Manf, anticorps RBM15B, anticorps manf, anticorps manf.S

Sujet: MANF, also known as ARMET, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors.More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF.In rat brain slices, MANF enhanced nigral gamma-aminobutyric acid release.Like GDNF and CDNF, MANF has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson's disease.Expression of MANF has also been shown to be induced during ER stress, suggesting that it may play a role in protein quality control during ER stress.
Synonyms: Mesencephalic astrocyte-derived neurotrophic factor, arginine-rich mutatedin early stage tumor, ARMET, ARP

UniProt: P55145