NLRP5 anticorps (C-Term)

N° du produit ABIN1886982

Détail du produit anti-NLRP5 anticorps

Antigène: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the carboxy terminus of human NALP5.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur NLRP5

Antigène: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Autre désignation: NALP5 (NLRP5 Produits)

Synonymes: anticorps CLR19.8, anticorps MATER, anticorps NALP5, anticorps PAN11, anticorps PYPAF8, anticorps Mater, anticorps Nalp5, anticorps Op1, anticorps NLR family pyrin domain containing 5, anticorps NLR family, pyrin domain containing 5, anticorps NLRP5, anticorps Nlrp5

Sujet: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction.NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice.Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
Synonyms: NLR family pyrin domain containing 5, NLRP5, MATER, PYRIN-containing APAF1-like protein 8, PYPAF8, CLR19.8, PAN11

NCBI Accession: NP_703148

Pathways: Inflammasome