BICD1 anticorps (C-Term)

N° du produit ABIN1887005

Détail du produit anti-BICD1 anticorps

Antigène: BICD1 (Bicaudal D Homolog 1 (BICD1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BICD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Specificité: At least two isoforms of BICD1 are known to exist, this antibody will only recognize the larger isoform.

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide from near the carboxy terminus of human BICD1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur BICD1

Antigène: BICD1 (Bicaudal D Homolog 1 (BICD1))

Autre désignation: BICD1 (BICD1 Produits)

Synonymes: anticorps BICD, anticorps B830009D06Rik, anticorps mKIAA4125, anticorps bicaudal D homolog 1 L homeolog, anticorps BICD cargo adaptor 1, anticorps bicaudal D homolog 1 (Drosophila), anticorps bicd1.L, anticorps BICD1, anticorps Bicd1

Sujet: BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis.BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport.BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain.Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells.
Synonyms: Bicaudal D homolog 1

NCBI Accession: NP_001705

Pathways: Ribonucleoprotein Complex Subunit Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, Maintenance of Protein Location