FGF4 anticorps (C-Term)

N° du produit ABIN1887254

Détail du produit anti-FGF4 anticorps

Antigène: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the carboxy terminus of the human FGF4.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur FGF4

Antigène: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Autre désignation: FGF4 (FGF4 Produits)

Synonymes: anticorps HBGF-4, anticorps HST, anticorps HST-1, anticorps HSTF1, anticorps K-FGF, anticorps KFGF, anticorps Fgf-4, anticorps Fgfk, anticorps Hst1, anticorps Hstf-1, anticorps KS3, anticorps hst, anticorps hst-1, anticorps kFGF, anticorps Hst, anticorps fibroblast growth factor 4, anticorps FGF4, anticorps Fgf4

Sujet: Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis.FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain.Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation.Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
Synonyms: Fibroblast growth factor 4, Heparin secretory-transforming protein, HST-1, HST, Transforming protein KS3, HBGF-4, Kaposi sarcoma oncogene

UniProt: P08620

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance