ECSIT anticorps (C-Term)

N° du produit ABIN1887360

Détail du produit anti-ECSIT anticorps

Antigène: ECSIT

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ECSIT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Ion exchange chromatography purified

Immunogène: Peptide corresponding to 14 amino acids near the C-terminus of human ECSIT.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur ECSIT

Antigène: ECSIT

Autre désignation: ECSIT (ECSIT Produits)

Synonymes: anticorps CG10610, anticorps DmECSIT, anticorps Dmel\\CG10610, anticorps dECSIT, anticorps ECSIT, anticorps Sitpec, anticorps SITPEC, anticorps CG10610 gene product from transcript CG10610-RA, anticorps ECSIT signalling integrator, anticorps ecsit, anticorps ECSIT signalling integrator S homeolog, anticorps ECSIT, anticorps CpipJ_CPIJ003637, anticorps Ecsit, anticorps ecsit.S

Sujet: Activation of NF-kappaB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses.Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6.ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway.Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.

NCBI Accession: NP_057665

Pathways: Signalisation TLR, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome