XIAP anticorps (C-Term)

N° du produit ABIN1887439

Détail du produit anti-XIAP anticorps

Antigène: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XIAP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: Synthetic peptide corresponding to 13 amino acids at the C-terminus of human XIAP.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur XIAP

Antigène: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Autre désignation: XIAP (XIAP Produits)

Synonymes: anticorps API3, anticorps BIRC4, anticorps IAP-3, anticorps ILP1, anticorps MIHA, anticorps XLP2, anticorps hIAP-3, anticorps hIAP3, anticorps api3, anticorps birc4, anticorps ilp1, anticorps miha, anticorps xlp2, anticorps xxiap, anticorps 1110015C02Rik, anticorps Aipa, anticorps Api3, anticorps Birc4, anticorps IAP3, anticorps ILP-1, anticorps mXIAP, anticorps riap3, anticorps fb73d01, anticorps wu:fb73d01, anticorps zgc:91873, anticorps BIRC8, anticorps X-linked inhibitor of apoptosis, anticorps X-linked inhibitor of apoptosis L homeolog, anticorps XIAP, anticorps xiap, anticorps xiap.L, anticorps Xiap

Sujet: Apoptosis, or programmed cell death, is related to many diseases, such as cancer.Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins.IAP proteins form a conserved gene family that binds to and inhibits cell death proteases.The X-chromosome linked inhibitor of apoptosis (XIAP) contains 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspases-3, -7, and -9.Upregulation of XIAP expression can protect cells from apoptosis induced by low level radiation, conversely, decreased XIAP expression by antisense targeting resulted in increased cell death following low level radiation.Two negative regulators, termed XAF-1 and Smac, can bind and inhibit XIAP activity.

NCBI Accession: NP_001158

Pathways: Apoptose, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis