C1QTNF2 anticorps (Center)

N° du produit ABIN1887585

Détail du produit anti-C1QTNF2 anticorps

Antigène: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1QTNF2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide from near the center of human CTRP2.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur C1QTNF2

Antigène: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Autre désignation: CTRP2 (C1QTNF2 Produits)

Synonymes: anticorps C1QTNF2, anticorps fe50b04, anticorps wu:fe50b04, anticorps CTRP2, anticorps zacrp2, anticorps 1810033K05Rik, anticorps Ctrp2, anticorps RGD1561041, anticorps C1q and tumor necrosis factor related protein 2, anticorps C1q and TNF related 2, anticorps C1QTNF2, anticorps c1qtnf2, anticorps C1qtnf2

Sujet: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines.One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7.Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues.These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism.An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene.Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin.Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.

NCBI Accession: NP_114114