CDIP1 anticorps (Center)

N° du produit ABIN1887614

Détail du produit anti-CDIP1 anticorps

Antigène: CDIP1 (LITAF-Like Protein (CDIP1))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDIP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the center of human CDIP.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur CDIP1

Antigène: CDIP1 (LITAF-Like Protein (CDIP1))

Autre désignation: CDIP (CDIP1 Produits)

Synonymes: anticorps RGD1310686, anticorps MGC165666, anticorps MGC97537, anticorps 2700048O17Rik, anticorps 5730403B10Rik, anticorps AU018521, anticorps AW742692, anticorps CDIP, anticorps C16orf5, anticorps I1, anticorps LITAFL, anticorps MGC52765, anticorps MGC127651, anticorps cell death-inducing p53 target 1, anticorps LITAF-like protein, anticorps cell death inducing Trp53 target 1, anticorps cell death inducing p53 target 1, anticorps cell death-inducing p53 target 1 L homeolog, anticorps Cdip1, anticorps cdip1, anticorps Bm1_00175, anticorps LOC100168843, anticorps CDIP1, anticorps cdip1.L

Sujet: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers.CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses.Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway.CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy.Multiple isoforms of CDIP are known to exist.
Synonyms: Cell death involved p53-target

NCBI Accession: NP_037531