Reticulon 4 anticorps (Center)

N° du produit ABIN1887705

Détail du produit anti-Reticulon 4 anticorps

Antigène: Reticulon 4 (RTN4)

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Reticulon 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: At least five isoforms of Nogo are known to exist, this antibody is specific for NogoA and NogoE.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide from near the center of human NogoA.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur Reticulon 4

Antigène: Reticulon 4 (RTN4)

Autre désignation: NogoA (RTN4 Produits)

Synonymes: anticorps ASY, anticorps NI220/250, anticorps NOGO, anticorps NOGO-A, anticorps NOGOC, anticorps NSP, anticorps NSP-CL, anticorps Nbla00271, anticorps Nbla10545, anticorps Nogo-B, anticorps Nogo-C, anticorps RTN-X, anticorps RTN4-A, anticorps RTN4-B1, anticorps RTN4-B2, anticorps RTN4-C, anticorps RTN4-Cw, anticorps DKFZp459C0314, anticorps 1110020G17Rik, anticorps AA407876, anticorps AA409940, anticorps AA960376, anticorps C130026I10Rik, anticorps NgA, anticorps Nogo-A, anticorps mKIAA0886, anticorps mKIAA4153, anticorps NI-250, anticorps Nogo, anticorps Vp20, anticorps r, anticorps rat N, anticorps rat NogoA, anticorps reticulon-4, anticorps nogo, anticorps rtn4, anticorps wu:fb17a02, anticorps wu:fb22f12, anticorps wu:fd61a07, anticorps zgc:92163, anticorps reticulon 4, anticorps reticulon 4a, anticorps RTN4, anticorps rtn4, anticorps Rtn4, anticorps rtn4a

Sujet: NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases.Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE.NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor.It is highly expressed in oligodendrocytes in the white matter of the CNS, blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models.NogoA has also been suggested to play a role in neurodegenerative diseases such as Amyotrophic lateral sclerosis, in which case NogoA is found at elevated levels in postmortem muscular samples, and multiple sclerosis (MS), in which case autoantibodies to NogoA have been found in serum and cerebrospinal fluid in MS patients.
Synonyms: Neurite outgrowth inhibitor A, reticulon 4, RTN4

NCBI Accession: NP_065393

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome