Clusterin anticorps (Isoform 1)

N° du produit ABIN1887800

Détail du produit anti-Clusterin anticorps

Antigène: Clusterin (CLU)

Épitope: Isoform 1

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Clusterin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Clusterin antibody was raised recombinant human Clusterin isoform 1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur Clusterin

Antigène: Clusterin (CLU)

Autre désignation: Clusterin (CLU Produits)

Synonymes: anticorps LOC100136120, anticorps clu, anticorps MGC53055, anticorps zgc:73352, anticorps xclu, anticorps MGC89163, anticorps CLU, anticorps APO-J, anticorps APOJ, anticorps CLI, anticorps CLU1, anticorps CLU2, anticorps KUB1, anticorps NA1/NA2, anticorps SGP-2, anticorps SGP2, anticorps SP-40, anticorps TRPM-2, anticorps TRPM2, anticorps DAG, anticorps RATTRPM2B, anticorps SP40, anticorps TRPM2B, anticorps Trpm2, anticorps Trpmb, anticorps AI893575, anticorps ApoJ, anticorps Cli, anticorps D14Ucla3, anticorps Sgp-2, anticorps Sgp2, anticorps Sugp-2, anticorps GP80, anticorps gpIII, anticorps 40, anticorps clusterin-1, anticorps clusterin L homeolog, anticorps clusterin, anticorps Clusterin, anticorps LOC100136120, anticorps clu.L, anticorps clu, anticorps CLU, anticorps clus, anticorps Clu, anticorps LOC101113728

Sujet: Clusterin, also known as Apolipoprotein J (ApoJ), is a ubiquitous multifunctional glycoprotein that can interact with a broad spectrum of molecules such as complement components, various receptors, and the Alzheimer's b-amyloid peptide.Clusterin expression is increased in Alzheimer's disease brain tissue and clusterin-immunoreactive amyloid plaques are found associated with phospho-tau-positive dystrophic neurites and it has been suggested that clusterin facilitates the conversion of diffuse b-amyloid deposits into amyloid and enhances tau phosphorylation in neurites around these plaques.Other reports show that clusterin expression is decreased in proliferating cells and is upregulated in quiescent and senescent cells, suggesting that it may also play a role in aging and tumorigenesis suppression.Clusterin exists in at least two distinct isoforms.
Synonyms: Clusterin, Complement lysis inhibitor, CLI, Apolipoprotein J, ApoJ

NCBI Accession: NP_001822

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling