CDC42 anticorps (N-Term)

N° du produit ABIN1888043

L’anticorps Lapin Polyclonal anti-CDC42 a été validé pour WB et ELISA. Il convient pour détecter CDC42 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CDC42 anticorps (N-Term) (ABIN1888043)

Antigène: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC42 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CDC42 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the amino terminus of human CDC42.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur CDC42

Antigène: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Autre désignation: CDC42

Sujet: CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression.This protein is highly similar to S.cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant.The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein.CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex.At least two isoforms of CDC42 are known to exist.
Synonyms: Cell division cycle 42, G25K

NCBI Accession: NP_001782

Pathways: Signalisation MAPK, Dynamique des Microtubules, Signalisation RTK, Signalisation WNT, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling