PCDH12 anticorps (N-Term)

N° du produit ABIN1888050

Détail du produit anti-PCDH12 anticorps

Antigène: PCDH12 (Protocadherin 12 (PCDH12))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDH12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): This antibody is predicted to not cross-react with PCDH18.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the amino terminus of human PCDH12.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur PCDH12

Antigène: PCDH12 (Protocadherin 12 (PCDH12))

Autre désignation: PCDH12 (PCDH12 Produits)

Synonymes: anticorps PCDH12, anticorps VE-cadherin-2, anticorps VECAD2, anticorps Pcdh14, anticorps VE-cad-2, anticorps protocadherin 12, anticorps PCDH12, anticorps Pcdh12

Sujet: Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules.Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA, further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta.PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice.Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.
Synonyms: Protocadherin 12, vascular endothelial cadherin 2, VE-cadherin 2, VECAD2

NCBI Accession: NP_057664

Pathways: Cellular Glucan Metabolic Process