NR1H4 anticorps (AA 1-476) (HRP)

N° du produit ABIN1991557

Détail du produit anti-NR1H4 anticorps (HRP)

Antigène: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Épitope: AA 1-476

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR1H4 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Bile acid receptor protein (1-476AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NR1H4

Antigène: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Autre désignation: NR1H4 (NR1H4 Produits)

Synonymes: anticorps zgc:110190, anticorps zgc:92742, anticorps NR1H4, anticorps BAR, anticorps FXR, anticorps HRR-1, anticorps HRR1, anticorps RIP14, anticorps AI957360, anticorps Fxr, anticorps Rxrip14, anticorps nuclear receptor subfamily 1, group H, member 5 S homeolog, anticorps nuclear receptor subfamily 1, group H, member 4, anticorps nuclear receptor subfamily 1 group H member 4, anticorps nr1h5.S, anticorps nr1h4, anticorps NR1H4, anticorps Nr1h4

Sujet:

Background: Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.

Aliases: BAR antibody, Bile acid receptor antibody, Farnesoid X activated receptor antibody, Farnesoid X receptor antibody, Farnesoid X-activated receptor antibody, Farnesol receptor HRR 1 antibody, Farnesol receptor HRR-1 antibody, Farnesol receptor HRR1 antibody, FXR antibody, HRR 1 antibody, HRR1 antibody, NR1H4 antibody, NR1H4_HUMAN antibody, Nuclear receptor subfamily 1 group H member 4 antibody, Retinoid X receptor interacting protein 14 antibody, Retinoid X receptor-interacting protein 14 antibody, RIP 14 antibody, RIP14 antibody, RXR interacting protein 14 antibody, RXR-interacting protein 14 antibody

UniProt: Q96RI1

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process