C3 anticorps
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- Antigène Voir toutes C3 Anticorps
- C3 (Complement Component 3 (C3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp C3 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Caprylic Acid Ammonium Sulfate Precipitation
- Immunogène
- Recombinant human Complement C3 protein
- Isotype
- IgG
- Top Product
- Discover our top product C3 Anticorps primaire
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- Indications d'application
- Optimal working concentration should be determinde by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze.
- Stock
- -20 °C/-80 °C
- Stockage commentaire
- Upon delivery aliquot and store at -20 °C or -80 °C.
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- Antigène
- C3 (Complement Component 3 (C3))
- Autre désignation
- Complement C3 (C3 Produits)
- Synonymes
- anticorps AHUS5, anticorps ARMD9, anticorps ASP, anticorps C3a, anticorps C3b, anticorps CPAMD1, anticorps AI255234, anticorps HSE-MSF, anticorps Plp, anticorps C3, anticorps C3-1, anticorps sb:cb26, anticorps si:dkey-76b14.4, anticorps wu:fi34b03, anticorps wu:fj86e11, anticorps C3d, anticorps asp, anticorps cpamd1, anticorps c3, anticorps complement C3, anticorps complement component 3, anticorps complement component c3a, duplicate 1, anticorps complement component 3 L homeolog, anticorps complement component C3, anticorps complement C3-like, anticorps C3, anticorps c3a.1, anticorps c3.L, anticorps LOC443475, anticorps c3, anticorps c3-1, anticorps LOC100060539
- Sujet
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C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Ref.5 Ref.11 Ref.14 Ref.15 Ref.16 Ref.22 Ref.25 Ref.30 Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Ref.5 Ref.11 Ref.14 Ref.15 Ref.16 Ref.22 Ref.25 Ref.30 Acylation stimulating protein (ASP): adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for GPR77. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of GPR77.
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1,C3,CPAMD1 - UniProt
- P01024
- Pathways
- Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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