IL-6 anticorps

N° du produit ABIN208765

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-6 dans WB et Neut. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour IL-6 anticorps (ABIN208765)

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-6 est non-conjugé

Application: Western Blotting (WB), Neutralization (Neut)

Détail du produit anti-IL-6 anticorps

Specificité: Reacts with natural and recombinant mouse interleukin 6 (IL-6) as assessed by ELISA. The antibody inhibits the biological activity of natural and recombinant mouse IL-6 as determined with the B9 cell bio-assay. The antibody cross-reacts with natural rat IL-6. IL-6 is a pluripotent 20-22 kD cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and hematopoiesis.

Purification: Purified

Immunogène:

Type of Immunogen: Native protein

Isotype: IgG

Information d'application

Indications d'application: Approved: Neut, WB (1:10)

Usage: Can be used for Neutralization of mouse and rat IL-6 in bio-assays. Furthermore the antibody is useful for Western Blot and immunoassay. Western Blot: 1:10. For neutralization of biological activity dilutions have to be made according to the amounts IL-6 to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, 0.1 % BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Détails sur IL-6

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Autre désignation: IL6

Sujet: Name/Gene ID: IL6
Family: Hormone

Synonyms: IL6, B-cell stimulatory factor 2, BSF-2, BSF2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, Interleukin-6, Interferon beta-2, Interleukin BSF-2, IFNB2, B-cell differentiation factor, CDF, HSF, IL-6

ID gène: 3569

UniProt: P05231

Pathways: Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome