IL-6 anticorps

N° du produit ABIN208766

L’anticorps anti-IL-6 Monoclonal Rat est utilisé pour la détection de IL-6 dans des échantillons de Souris. Il a été validé pour Neut et Func.

Aperçu rapide pour IL-6 anticorps (ABIN208766)

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 est non-conjugé

Application: Neutralization (Neut), Functional Studies (Func)

Détail du produit anti-IL-6 anticorps

Specificité: Neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNF-alpha nor does it bind to either human or rat IL-6. Inhibits IL-6 induced proliferation of the B9 assay.

Purification: Purified

Immunogène:

Type of Immunogen: Native protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: Func, Neut

Usage: Can be used for in vitro and in vivo inhibition of activity of IL-6. Furthermore the antibody is useful for Immunochemical investigations of mouse IL-6 in structural studies and for quantitative/qualitative immunochemical detection methods. May be used as a coating antibody in immunoassay procedures. For neutralization of biological activity dilutions have to be made according to the amount of IL-6 to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, 0.1 % BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Détails sur IL-6

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Autre désignation: IL6

Sujet: Name/Gene ID: IL6
Family: Hormone

Synonyms: IL6, B-cell stimulatory factor 2, BSF-2, BSF2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, Interleukin-6, Interferon beta-2, Interleukin BSF-2, IFNB2, B-cell differentiation factor, CDF, HSF, IL-6

ID gène: 3569

UniProt: P05231

Pathways: Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome