TNFRSF10B anticorps (AA 131-230)

N° du produit ABIN2173759

Détail du produit anti-TNFRSF10B anticorps

Antigène: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Épitope: AA 131-230

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF10B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DR5/CD262

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TNFRSF10B

Antigène: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Autre désignation: DR5 (TNFRSF10B Produits)

Synonymes: anticorps TNFRSF10B, anticorps dr5, anticorps cd262, anticorps killer, anticorps trick2, anticorps trickb, anticorps xDR-M1, anticorps xDR-M2, anticorps ztnfr9, anticorps trailr2, anticorps trick2a, anticorps trick2b, anticorps CD262, anticorps DR5, anticorps KILLER, anticorps KILLER/DR5, anticorps TRAIL-R2, anticorps TRAILR2, anticorps TRICK2, anticorps TRICK2A, anticorps TRICK2B, anticorps TRICKB, anticorps ZTNFR9, anticorps Ly98, anticorps MK, anticorps tumor necrosis factor receptor superfamily, member 10b, anticorps tumor necrosis factor receptor superfamily member 10b S homeolog, anticorps tumor necrosis factor receptor superfamily member 10b L homeolog, anticorps tumor necrosis factor receptor superfamily member 10b, anticorps TNF receptor superfamily member 10b, anticorps Tnfrsf10b, anticorps TNFRSF10B, anticorps tnfrsf10b.S, anticorps tnfrsf10b.L, anticorps tnfrsf10b

Sujet:

Synonyms: Death receptor 5, CD 262, CD262, CD262 antigen, Death domain containing receptor for TRAIL/Apo2L, Death receptor 5, DR 5, DR5, Fas like protein precursor, KILLER, KILLER/DR5, p53 regulated DNA damage inducible cell death receptor (killer), TNF related apoptosis inducing ligand receptor 2, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL R2, TRAIL receptor 2, TRAILR2, TRANCER, TRICK2, TRICK2A, TRICK2B, TRICKB, Tumor necrosis factor receptor like protein ZTNFR9, Tumor necrosis factor receptor superfamily member 10b, ZTNFR9.

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Pathways: Signalisation p53, Apoptose, Positive Regulation of Endopeptidase Activity