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Histone 3 anticorps (acLys10, pSer11) (HRP)

H3 Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN2175109
  • Antigène Voir toutes Histone 3 (H3) Anticorps
    Histone 3 (H3)
    Épitope
    • 60
    • 47
    • 44
    • 44
    • 41
    • 36
    • 35
    • 35
    • 34
    • 34
    • 34
    • 32
    • 29
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    • 12
    • 12
    • 11
    • 11
    • 11
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    acLys10, pSer11
    Reactivité
    • 1376
    • 940
    • 861
    • 59
    • 42
    • 41
    • 41
    • 40
    • 39
    • 35
    • 35
    • 30
    • 26
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 1183
    • 246
    • 12
    • 4
    Lapin
    Clonalité
    • 1108
    • 336
    • 1
    Polyclonal
    Conjugué
    • 798
    • 81
    • 48
    • 47
    • 45
    • 45
    • 45
    • 45
    • 34
    • 32
    • 22
    • 18
    • 18
    • 18
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 12
    • 1
    Cet anticorp Histone 3 est conjugé à/à la HRP
    Application
    • 1034
    • 401
    • 373
    • 311
    • 240
    • 188
    • 175
    • 171
    • 163
    • 151
    • 137
    • 127
    • 116
    • 47
    • 38
    • 34
    • 32
    • 20
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Cow,Pig,Rabbit,Drosophila
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Acetyl and Histone H3 (Ac-Lys10/p-Ser11)
    Isotype
    IgG
    Top Product
    Discover our top product H3 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Histone 3 (H3)
    Autre désignation
    Histone H3 (H3 Produits)
    Synonymes
    anticorps H-3, anticorps histocompatibility 3, anticorps H3
    Sujet

    Synonyms: H3 histone family member E pseudogene, H3F3, HIST3H3, Histone H3 3 pseudogene.

    Background: Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.

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