TNFRSF1A anticorps

N° du produit ABIN2191868

Détail du produit anti-TNFRSF1A anticorps

Antigène: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF1A est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA), Agonist (Agon), Cell Culture (CC)

Stérilité: 0.2 μm filtered

Clone: MR1-2

Information d'application

Indications d'application: For immunohistology and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. Advised positive controls for frozen sections are human lymphnodes and for flow cytometry PHA activated T cells.

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Date de péremption: 12 months

Références pour anticorps anti-TNFRSF1A (ABIN2191868)

Leeuwenberg, Dentener, Buurman: "Lipopolysaccharide LPS-mediated soluble TNF receptor release and TNF receptor expression by monocytes. Role of CD14, LPS binding protein, and bactericidal/permeability-increasing protein." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 10, pp. 5070-6, (1994) (PubMed).

Détails sur TNFRSF1A

Antigène: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Autre désignation: Cd120a, Tnf-R I (TNFRSF1A Produits)

Synonymes: anticorps CD120a, anticorps FPF, anticorps MS5, anticorps TBP1, anticorps TNF-R, anticorps TNF-R-I, anticorps TNF-R55, anticorps TNFAR, anticorps TNFR1, anticorps TNFR1-d2, anticorps TNFR55, anticorps TNFR60, anticorps p55, anticorps p55-R, anticorps p60, anticorps TNF-R1, anticorps TNF-alphaR1, anticorps TNFRI, anticorps TNFRp55, anticorps TNFalpha-R1, anticorps Tnfr-2, anticorps Tnfr1, anticorps fpf, anticorps tbp1, anticorps p55-r, anticorps tnf-r, anticorps tnfar, anticorps tnfr1, anticorps cd120a, anticorps tnfr55, anticorps tnfr60, anticorps xtnfr1, anticorps wu:fj65b10, anticorps zgc:85914, anticorps TNFR I, anticorps TNFRSF1A, anticorps TNFA, anticorps cTNF, anticorps TNF receptor superfamily member 1A, anticorps tumor necrosis factor receptor superfamily, member 1a, anticorps TNF receptor superfamily member 1A S homeolog, anticorps tumor necrosis factor, anticorps TNFRSF1A, anticorps Tnfrsf1a, anticorps tnfrsf1a.S, anticorps tnfrsf1a, anticorps TNF

Sujet: The antibody MR1-2 reacts with the extra-cellular part of the TNF-R I. It also reacts with the soluble receptor. TNF-R I is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha: Induction of cytotoxicity and other functions are mediated largely via TNF-R I. The antibody cross reacts with rhesus and cynomolgus natural TNF-R I.

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway