PKC alpha anticorps (pThr638, Thr641)

N° du produit ABIN220827

Détail du produit anti-PKC alpha anticorps

Antigène: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Épitope: pThr638, Thr641

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC alpha est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Specificité: Detects human PKC alpha only when phosphorylated at Thr638 and human PKC beta II only when phosphorylated at Thr641. Reacts weakly with phosphorylated PKC beta I and gamma. Recognizes the active form of PKC. Species cross-reactivity: Monkey and mouse. Predicted to cross-react with rat based on sequence homology.

Purification: Protein A purified

Immunogène: Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Thr638 of human PKC alpha.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: ELISA, IP (1:100), WB (1:1000)

Usage: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:1000. Immunoprecipitation: 1:100.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur PKC alpha

Antigène: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Autre désignation: PRKCA / PKC-Alpha (PKCa Produits)

Synonymes: anticorps pkc-alpha, anticorps pkcalpha, anticorps im:7139045, anticorps si:dkey-8l19.1, anticorps LOC100219195, anticorps AAG6, anticorps PKC-alpha, anticorps PKCA, anticorps PRKACA, anticorps AI875142, anticorps Pkca, anticorps PKRCA, anticorps protein kinase C alpha, anticorps protein kinase C, alpha L homeolog, anticorps protein kinase C, alpha, anticorps PRKCA, anticorps prkca.L, anticorps prkca, anticorps Prkca

Sujet: Name/Gene ID: PRKCA
Subfamily: PKC
Family: Protein Kinase

Synonyms: PRKCA, Aging-associated gene 6, AAG6, Alpha PKC, PKC-A, Pkcalpha, Protein kinase C alpha type, PKC Alpha, PKC-alpha, PKCA, Protein kinase c alpha, Protein kinase C, alpha

ID gène: 5578

UniProt: P17252

Pathways: Signalisation WNT, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling