Aurora Kinase B anticorps (AA 227-238)
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- Antigène Voir toutes Aurora Kinase B (AURKB) Anticorps
- Aurora Kinase B (AURKB)
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Épitope
- AA 227-238
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Aurora Kinase B est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- Detects Aurora-B kinase (AurB), a serine/threonine kinase which is the enzymatic core of the Chromosomal Passenger Complex (CPC). This complex functions in chromosome alignment and separation, histone modification, and cytokinesis. CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB. Two CPCs exist during mitosis- one containing all four members, and another consisting of INCENP and AurB. Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3. AurB is overexpressed in a number of tumors, including primary breast and colon tumor samples. Its expression in tumors seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.
- Purification
- Purified
- Immunogène
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Synthetic peptide corresponding to amino acids 227-238 of human Aurora-B kinase.
Type of Immunogen: Synthetic peptide - Isotype
- IgG
- Top Product
- Discover our top product AURKB Anticorps primaire
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- Indications d'application
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Approved: ELISA (1:2000 - 1:10000), WB (1:250 - 1:1000)
Usage: Western Blot: LS-C42572 detects a band of approximately 39kD in HeLa cell lysates. - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.2, 0.01 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Antigène
- Aurora Kinase B (AURKB)
- Autre désignation
- AURKB / Aurora-B (AURKB Produits)
- Synonymes
- anticorps AIK2, anticorps AIM-1, anticorps AIM1, anticorps ARK2, anticorps AurB, anticorps IPL1, anticorps PPP1R48, anticorps STK12, anticorps STK5, anticorps aurkb-sv1, anticorps aurkb-sv2, anticorps AIRK2, anticorps AL022959, anticorps Aik2, anticorps Aim1, anticorps Ark2, anticorps STK-1, anticorps Stk12, anticorps Stk5, anticorps Aur B, anticorps Aurora B, anticorps Aurora-B, anticorps CG6620, anticorps DmAIRK2, anticorps DmAurB, anticorps DmAuroraB, anticorps Dmel\\CG6620, anticorps IAL, anticorps IAL1, anticorps Ial, anticorps aurB, anticorps aurora B, anticorps ARK-2, anticorps XAIRK2, anticorps aik2, anticorps aim-1, anticorps aim1, anticorps airk2, anticorps ark2, anticorps ipl1, anticorps stk12, anticorps stk5, anticorps CHUNP6896, anticorps fa09g06, anticorps stka, anticorps wu:fa09g06, anticorps aurkb, anticorps AIRK2-B, anticorps XAIRK2-B, anticorps aurkb-a, anticorps aurkb-b, anticorps xAurora-B-B, anticorps aurora kinase B, anticorps aurora B, anticorps aurora kinase B S homeolog, anticorps AURKB, anticorps Aurkb, anticorps aurB, anticorps aurkb, anticorps aurkb.S
- Sujet
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Name/Gene ID: AURKB
Subfamily: Aurora/IPL1-like
Family: Protein Kinase
Synonyms: AURKB, AIRK2, AIK2, Aurora kinase B, Aurora kinase B-Sv1, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, ARK-2, ARK2, Aurkb-sv1, Aurkb-sv2, Aurora 1, Aurora-B, AIM-1, IPL1, STK-1, STK5, PPP1R48, AurB, Aurora B, Aurora kinase B-Sv2, Aurora-1, Aurora1, Serine/threonine kinase 12, STK1, STK12 - ID gène
- 9212
- UniProt
- Q96GD4
- Pathways
- TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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