anticorps cb984, anticorps ptprm, anticorps zgc:110218, anticorps PTPRM, anticorps p-ptp-mu, anticorps ptprl1, anticorps r-ptpu, anticorps rptpm, anticorps rptpu, anticorps PTPRL1, anticorps R-PTP-MU, anticorps RPTPM, anticorps RPTPU, anticorps hR-PTPu, anticorps RPTPmu, anticorps mKIAA4044, anticorps protein tyrosine phosphatase, receptor type, M, a, anticorps protein tyrosine phosphatase, receptor type M, anticorps protein tyrosine phosphatase, receptor type, M, b, anticorps receptor-type tyrosine-protein phosphatase mu, anticorps protein tyrosine phosphatase, receptor type, M, anticorps ptprma, anticorps PTPRM, anticorps ptprmb, anticorps ptprm, anticorps LOC100550127, anticorps LOC100564083, anticorps Ptprm
Sujet
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.