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CD59 anticorps

CD59 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2434430
  • Antigène Voir toutes CD59 Anticorps
    CD59
    Reactivité
    • 139
    • 14
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 91
    • 69
    • 6
    • 4
    Lapin
    Clonalité
    • 98
    • 69
    • 1
    Polyclonal
    Conjugué
    • 79
    • 21
    • 16
    • 13
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD59 est non-conjugé
    Application
    • 102
    • 70
    • 46
    • 41
    • 31
    • 28
    • 25
    • 15
    • 15
    • 14
    • 13
    • 12
    • 11
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purification
    Affinity purification
    Immunogène
    Synthetic peptide of human CD59
    Isotype
    IgG
    Top Product
    Discover our top product CD59 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:100-1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Agent conservateur
    Sodium azide
    Conseil sur la manipulation
    Avoid freeze / thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CD59
    Autre désignation
    CD59 (CD59 Produits)
    Synonymes
    anticorps 16.3A5, anticorps 1F5, anticorps EJ16, anticorps EJ30, anticorps EL32, anticorps G344, anticorps HRF-20, anticorps HRF20, anticorps MAC-IP, anticorps MACIF, anticorps MEM43, anticorps MIC11, anticorps MIN1, anticorps MIN2, anticorps MIN3, anticorps MIRL, anticorps MSK21, anticorps p18-20, anticorps Cd59a, anticorps Cd59b, anticorps MACIP, anticorps CD59 molecule (CD59 blood group), anticorps CD59 molecule, anticorps CD59, anticorps Cd59
    Sujet
    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
    Poids moléculaire
    Calculated MW: 14 kDa
    NCBI Accession
    NP_000602
    Pathways
    Système du Complément
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