ZFPM1 anticorps

N° du produit ABIN2457936

Détail du produit anti-ZFPM1 anticorps

Antigène: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZFPM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZFPM1.

Information d'application

Indications d'application: ZFPM1 antibody can be used for detection of ZFPM1 by ELISA at 1:62500. ZFPM1 antibody can be used for detection of ZFPM1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZFPM1 antibody at -20 °C.

Détails sur ZFPM1

Antigène: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Autre désignation: ZFPM1 (ZFPM1 Produits)

Synonymes: anticorps FOG, anticorps FOG1, anticorps ZC2HC11A, anticorps ZNF408, anticorps ZNF89A, anticorps Fog1, anticorps Xfog, anticorps fog, anticorps fog-1, anticorps fog1, anticorps FOG-1, anticorps si:dkey-20g6.1, anticorps si:dkey-38l12.1, anticorps ZNF469, anticorps ZFPM1, anticorps zinc finger protein, FOG family member 1, anticorps zinc finger protein, multitype 1, anticorps zinc finger protein, FOG family member 1 L homeolog, anticorps ZFPM1, anticorps Zfpm1, anticorps zfpm1.L, anticorps zfpm1

Sujet: ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.

Poids moléculaire: 105 kDa

ID gène: 161882

NCBI Accession: NP_722520

UniProt: Q8IX07