ISL1 anticorps

N° du produit ABIN2457943

Détail du produit anti-ISL1 anticorps

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ISL1.

Information d'application

Indications d'application: ISL1 antibody can be used for detection of ISL1 by ELISA at 1:312500. ISL1 antibody can be used for detection of ISL1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ISL1 antibody at -20 °C.

Détails sur ISL1

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Autre désignation: ISL1 (ISL1 Produits)

Synonymes: anticorps Xisl-1, anticorps Xislet-1, anticorps islet1, anticorps ISLET-1, anticorps ISLET1, anticorps Isl-1, anticorps islet-1, anticorps isl-1=homeobox, anticorps Islet-1, anticorps ISL LIM homeobox 1 S homeolog, anticorps ISL LIM homeobox 1, anticorps ISL1 transcription factor, LIM/homeodomain, anticorps isl1.S, anticorps ISL1, anticorps Isl1, anticorps isl1

Sujet: ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 39 kDa

ID gène: 3670

NCBI Accession: NP_002193

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding