RFC4 anticorps

N° du produit ABIN2458986

Détail du produit anti-RFC4 anticorps

Antigène: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFC4 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RFC4.

Information d'application

Indications d'application: RFC4 antibody can be used for detection of RFC4 by ELISA at 1:62500. RFC4 antibody can be used for detection of RFC4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RFC4 antibody at -20 °C.

Détails sur RFC4

Antigène: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Autre désignation: RFC4 (RFC4 Produits)

Synonymes: anticorps 44.t00003, anticorps 21.m03053, anticorps rfc4, anticorps A1, anticorps AI894123, anticorps AU040575, anticorps RFC37, anticorps rfc2, anticorps replication factor C subunit 4, anticorps Replication factor C subunit 4, anticorps replication factor C (activator 1) 4, anticorps replication factor C subunit 4 L homeolog, anticorps PFL2005w, anticorps EHI_167150, anticorps TP03_0432, anticorps Tb11.01.1310, anticorps BBOV_IV002210, anticorps rfc4, anticorps rfc-4, anticorps Rfc4, anticorps RFC4, anticorps rfc4.L

Sujet: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.

Poids moléculaire: 40 kDa

ID gène: 5984

NCBI Accession: NP_002907

UniProt: P35249

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA