VPS4A anticorps

N° du produit ABIN2459830

Détail du produit anti-VPS4A anticorps

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS4A est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VPS4A.

Information d'application

Indications d'application: VPS4A antibody can be used for detection of VPS4A by ELISA at 1:312500. VPS4A antibody can be used for detection of VPS4A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store VPS4A antibody at -20 °C.

Détails sur VPS4A

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Autre désignation: VPS4A (VPS4A Produits)

Synonymes: anticorps vsp4, anticorps SKD1, anticorps SKD1A, anticorps SKD2, anticorps VPS4, anticorps VPS4-1, anticorps zgc:153907, anticorps 4930589C15Rik, anticorps AI325971, anticorps AW553189, anticorps vacuolar protein sorting 4 homolog A, anticorps vacuolar sorting protein 4, anticorps vacuolar protein sorting 4 homolog A L homeolog, anticorps vacuolar protein sorting 4a homolog A (S. cerevisiae), anticorps vacuolar protein sorting 4A, anticorps VPS4A, anticorps TP03_0351, anticorps vps4a, anticorps vps4a.L, anticorps Vps4a

Sujet: VPS4A is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast.The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 49 kDa

ID gène: 27183

NCBI Accession: NP_037377

UniProt: Q9UN37

Pathways: Dynamique des Microtubules, CXCR4-mediated Signaling Events