Cyclin H anticorps

N° du produit ABIN2460141

Détail du produit anti-Cyclin H anticorps

Antigène: Cyclin H (CCNH)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin H est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCNH.

Information d'application

Indications d'application: CCNH antibody can be used for detection of CCNH by ELISA at 1:1562500. CCNH antibody can be used for detection of CCNH by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CCNH antibody at -20 °C.

Détails sur Cyclin H

Antigène: Cyclin H (CCNH)

Autre désignation: CCNH (CCNH Produits)

Synonymes: anticorps zgc:114132, anticorps cak, anticorps p34, anticorps p37, anticorps Cych, anticorps ACYPI004637, anticorps ccnh, anticorps Cyclin-H, anticorps 142767_at, anticorps CG7405, anticorps Dmel\\CG7405, anticorps CAK, anticorps 6330408H09Rik, anticorps AI661354, anticorps AV102684, anticorps AW538719, anticorps ccnh-A, anticorps cyclin H, anticorps cyclin-H, anticorps Cyclin H, anticorps CYclin H, anticorps cyclin H L homeolog, anticorps CCNH, anticorps ccnh, anticorps LOC5577539, anticorps Cych, anticorps CycH, anticorps cyh-1, anticorps Ccnh, anticorps ccnh.L

Sujet: CCNH belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 38 kDa

ID gène: 902

NCBI Accession: NP_001230

UniProt: P51946

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase