DREAM anticorps

N° du produit ABIN2460323

Détail du produit anti-DREAM anticorps

Antigène: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DREAM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CSEN.

Information d'application

Indications d'application: CSEN antibody can be used for detection of CSEN by ELISA at 1:12500. CSEN antibody can be used for detection of CSEN by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CSEN antibody at -20 °C.

Détails sur DREAM

Antigène: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Autre désignation: CSEN (KCNIP3 Produits)

Synonymes: anticorps CSEN, anticorps DREAM, anticorps KCHIP3, anticorps 4933407H12Rik, anticorps AI413860, anticorps Csen, anticorps KChIP3, anticorps R74849, anticorps Dream, anticorps rKChIP3, anticorps csen, anticorps im:7145308, anticorps kcnip3, anticorps zgc:73306, anticorps KCNIP3, anticorps potassium voltage-gated channel interacting protein 3, anticorps Kv channel-interacting protein 4, anticorps calsenilin, anticorps Kv channel interacting protein 3, calsenilin, anticorps Kv channel interacting protein 3b, calsenilin, anticorps KCNIP3, anticorps LOC5568664, anticorps CpipJ_CPIJ002549, anticorps Tsp_05009, anticorps Kcnip3, anticorps kcnip3b, anticorps kcnip3

Sujet: CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.

Poids moléculaire: 29 kDa

ID gène: 30818

NCBI Accession: NP_038462

UniProt: Q9Y2W7