MCM3 anticorps
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- Antigène Voir toutes MCM3 Anticorps
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MCM3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MCM3.
- Top Product
- Discover our top product MCM3 Anticorps primaire
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- Indications d'application
- MCM3 antibody can be used for detection of MCM3 by ELISA at 1:12500. MCM3 antibody can be used for detection of MCM3 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store MCM3 antibody at -20 °C.
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- Antigène
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
- Autre désignation
- MCM3 (MCM3 Produits)
- Synonymes
- anticorps HCC5, anticorps P1-MCM3, anticorps P1.h, anticorps RLFB, anticorps AL033361, anticorps C80350, anticorps Mcmd, anticorps P1, anticorps p1.m, anticorps cb32, anticorps chunp6867, anticorps wu:fa26g03, anticorps CG4206, anticorps DmMCM3, anticorps DmMcm3, anticorps DmeMCM3, anticorps Dmel\\CG4206, anticorps MCM3, anticorps McM3, anticorps Mcp-PCR2, anticorps PCR2, anticorps dMCM3, anticorps xmcm3, anticorps minichromosome maintenance complex component 3, anticorps MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), anticorps Minichromosome maintenance 3, anticorps minichromosome maintenance complex component 3 L homeolog, anticorps MCM complex subunit Mcm3, anticorps MCM3, anticorps mcm3, anticorps Mcm3, anticorps mcm3.L
- Sujet
- MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
- Poids moléculaire
- 89 kDa
- ID gène
- 4172
- NCBI Accession
- NP_002379
- UniProt
- P25205
- Pathways
- Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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