NFIL3 anticorps
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- Antigène Voir toutes NFIL3 Anticorps
- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFIL3 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFIL3.
- Top Product
- Discover our top product NFIL3 Anticorps primaire
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- Indications d'application
- NFIL3 antibody can be used for detection of NFIL3 by ELISA at 1:312500. NFIL3 antibody can be used for detection of NFIL3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFIL3 antibody at -20 °C.
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- Antigène
- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
- Autre désignation
- NFIL3 (NFIL3 Produits)
- Synonymes
- anticorps e4bp4, anticorps il3bp1, anticorps nfil3a, anticorps nf-il3a, anticorps MGC107826, anticorps NFIL3, anticorps E4BP4, anticorps IL3BP1, anticorps NF-IL3A, anticorps NFIL3A, anticorps E4BP4-1, anticorps zgc:100867, anticorps AV225605, anticorps nuclear factor, interleukin 3 regulated, anticorps nuclear factor, interleukin 3 regulated L homeolog, anticorps nuclear factor, interleukin 3, regulated, anticorps nfil3, anticorps NFIL3, anticorps Nfil3, anticorps nfil3.L
- Sujet
- NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
- Poids moléculaire
- 51 kDa
- ID gène
- 4783
- NCBI Accession
- NP_005375
- UniProt
- Q14211
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