NFIL3 anticorps

N° du produit ABIN2461756

Détail du produit anti-NFIL3 anticorps

Antigène: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFIL3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFIL3.

Information d'application

Indications d'application: NFIL3 antibody can be used for detection of NFIL3 by ELISA at 1:312500. NFIL3 antibody can be used for detection of NFIL3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFIL3 antibody at -20 °C.

Détails sur NFIL3

Antigène: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Autre désignation: NFIL3 (NFIL3 Produits)

Synonymes: anticorps e4bp4, anticorps il3bp1, anticorps nfil3a, anticorps nf-il3a, anticorps MGC107826, anticorps NFIL3, anticorps E4BP4, anticorps IL3BP1, anticorps NF-IL3A, anticorps NFIL3A, anticorps E4BP4-1, anticorps zgc:100867, anticorps AV225605, anticorps nuclear factor, interleukin 3 regulated, anticorps nuclear factor, interleukin 3 regulated L homeolog, anticorps nuclear factor, interleukin 3, regulated, anticorps nfil3, anticorps NFIL3, anticorps Nfil3, anticorps nfil3.L

Sujet: NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.

Poids moléculaire: 51 kDa

ID gène: 4783

NCBI Accession: NP_005375

UniProt: Q14211