HIF3A anticorps

N° du produit ABIN2461997

Détail du produit anti-HIF3A anticorps

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIF3A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HIF3A.

Information d'application

Indications d'application: HIF3A antibody can be used for detection of HIF3A by ELISA at 1:312500. HIF3A antibody can be used for detection of HIF3A by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HIF3A antibody at -20 °C.

Détails sur HIF3A

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Autre désignation: HIF3A (HIF3A Produits)

Synonymes: anticorps HIF-3A, anticorps IPAS, anticorps MOP7, anticorps PASD7, anticorps bHLHe17, anticorps Ipas, anticorps NEPAS, anticorps Mop7, anticorps HIF3A, anticorps hypoxia inducible factor 3 alpha subunit, anticorps hypoxia inducible factor 3, alpha subunit, anticorps HIF3A, anticorps Hif3a

Sujet: HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.

Poids moléculaire: 72 kDa, 66 kDa, 72 kDa

ID gène: 64344

NCBI Accession: NP_690007

UniProt: Q9Y2N7

Pathways: L'effet Warburg