FZD7 anticorps

N° du produit ABIN2462375

Détail du produit anti-FZD7 anticorps

Antigène: FZD7 (Frizzled Family Receptor 7 (FZD7))

Reactivité: Humain, Souris, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FZD7.

Information d'application

Indications d'application: FZD7 antibody can be used for detection of FZD7 by ELISA at 1:1562500. FZD7 antibody can be used for detection of FZD7 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FZD7 antibody at -20 °C.

Détails sur FZD7

Antigène: FZD7 (Frizzled Family Receptor 7 (FZD7))

Autre désignation: FZD7 (FZD7 Produits)

Synonymes: anticorps FzE3, anticorps Fz-7, anticorps Xfz7, anticorps frizzled-7, anticorps frizzled7, anticorps frz-7, anticorps frz7, anticorps fz7, anticorps fzd7-a, anticorps fzd7-b, anticorps fze3, anticorps Fz7, anticorps cFz-7, anticorps fb38g02, anticorps fc44b09, anticorps fz13, anticorps fz7a, anticorps fz7b, anticorps wu:fb38g02, anticorps wu:fc44b09, anticorps zg13, anticorps frizzled class receptor 7, anticorps frizzled class receptor 7 L homeolog, anticorps frizzled class receptor 7b, anticorps FZD7, anticorps fzd7.L, anticorps fzd7, anticorps Fzd7, anticorps fzd7b

Sujet: FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Poids moléculaire: 63 kDa

ID gène: 8324

NCBI Accession: NP_003498

UniProt: O75084

Pathways: Signalisation WNT, Stem Cell Maintenance