Growth Hormone 2 anticorps

N° du produit ABIN2462514

Détail du produit anti-Growth Hormone 2 anticorps

Antigène: Growth Hormone 2 (GH2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Growth Hormone 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GH2.

Information d'application

Indications d'application: GH2 antibody can be used for detection of GH2 by ELISA at 1:312500. GH2 antibody can be used for detection of GH2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GH2 antibody at -20 °C.

Détails sur Growth Hormone 2

Antigène: Growth Hormone 2 (GH2)

Autre désignation: GH2 (GH2 Produits)

Synonymes: anticorps GH-V, anticorps GHL, anticorps GHV, anticorps hGH-V, anticorps growth hormone 2, anticorps GH2

Sujet: GH2 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Mutations in its gene lead to placental growth hormone/lactogen deficiency.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency.

Poids moléculaire: 22 kDa, 25 kDa

ID gène: 2689

NCBI Accession: NP_072050

UniProt: O14643

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Response to Growth Hormone Stimulus