RNF128 anticorps

N° du produit ABIN2462682

Détail du produit anti-RNF128 anticorps

Antigène: RNF128 (Ring Finger Protein 128 (RNF128))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF128 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF128.

Information d'application

Indications d'application: RNF128 antibody can be used for detection of RNF128 by ELISA at 1:312500. RNF128 antibody can be used for detection of RNF128 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RNF128 antibody at -20 °C.

Détails sur RNF128

Antigène: RNF128 (Ring Finger Protein 128 (RNF128))

Autre désignation: RNF128 (RNF128 Produits)

Synonymes: anticorps rnf128, anticorps wu:fb57h05, anticorps zgc:77843, anticorps 1300002C13Rik, anticorps AI987883, anticorps GRAIL, anticorps Greul1, anticorps RGD1566282, anticorps grail, anticorps greul1, anticorps ring finger protein 128a, anticorps ring finger protein 128, E3 ubiquitin protein ligase, anticorps ring finger protein 128, anticorps ring finger protein 128, E3 ubiquitin protein ligase L homeolog, anticorps rnf128a, anticorps RNF128, anticorps Rnf128, anticorps rnf128.L

Sujet: RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4 (+) T cells, which suggested a role in the induction of anergic phenotype.The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4 (+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 47 kDa, 45 kDa

ID gène: 79589

NCBI Accession: NP_919445

UniProt: Q8TEB7