MRPS12 anticorps

N° du produit ABIN2462968

Détail du produit anti-MRPS12 anticorps

Antigène: MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRPS12 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MRPS12.

Information d'application

Indications d'application: MRPS12 antibody can be used for detection of MRPS12 by ELISA at 1:1562500. MRPS12 antibody can be used for detection of MRPS12 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MRPS12 antibody at -20 °C.

Détails sur MRPS12

Antigène: MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

Autre désignation: MRPS12 (MRPS12 Produits)

Synonymes: anticorps MPR-S12, anticorps MT-RPS12, anticorps RPMS12, anticorps RPS12, anticorps RPSM12, anticorps AI327385, anticorps Rpms12, anticorps rps12, anticorps CG7925, anticorps Dmel\\CG7925, anticorps EG:BACH59J11.1, anticorps MRP-S12, anticorps MRPS12, anticorps S12, anticorps Tko, anticorps l(1)3Ab, anticorps l(1)tko, anticorps mRpS12, anticorps mt-rps12, anticorps MGC64304, anticorps GB10531, anticorps mitochondrial ribosomal protein S12, anticorps technical knockout, anticorps mitochondrial ribosomal protein S12 L homeolog, anticorps 40S ribosomal protein S12, mitochondrial, anticorps putative mitochondrial 37S ribosomal protein MRPS12, anticorps fragile site, aphidicolin type, common, fra(6)(p22.2), anticorps MRPS12, anticorps Mrps12, anticorps tko, anticorps mrps12.L, anticorps LOC409723, anticorps mRpS12, anticorps mrps12, anticorps CAALFM_C106070WA, anticorps mrpS12, anticorps FRA6C

Sujet: Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPS12 is the 28S subunit protein that belongs to the ribosomal protein S12P family. The protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics.Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same protein.

Poids moléculaire: 12 kDa

ID gène: 6183

NCBI Accession: NP_066930

UniProt: O15235

Pathways: Sensory Perception of Sound