ZMPSTE24 anticorps

N° du produit ABIN2462996

Détail du produit anti-ZMPSTE24 anticorps

Antigène: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZMPSTE24 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZMPSTE24.

Information d'application

Indications d'application: ZMPSTE24 antibody can be used for detection of ZMPSTE24 by ELISA at 1:312500. ZMPSTE24 antibody can be used for detection of ZMPSTE24 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZMPSTE24 antibody at -20 °C.

Détails sur ZMPSTE24

Antigène: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Autre désignation: ZMPSTE24 (Zmpste24 Produits)

Synonymes: anticorps DDBDRAFT_0189115, anticorps DDBDRAFT_0237846, anticorps DDB_0189115, anticorps DDB_0237846, anticorps F2N1.21, anticorps F2N1_21, anticorps STE24, anticorps FACE-1, anticorps FACE1, anticorps HGPS, anticorps PRO1, anticorps Ste24p, anticorps A530043O15Rik, anticorps D030046F19, anticorps Face-1, anticorps MADB, anticorps fi45a02, anticorps wu:fi45a02, anticorps zgc:55655, anticorps zinc metallopeptidase STE24, anticorps zinc metallopeptidase STE24 L homeolog, anticorps CAAX prenyl protease, anticorps Peptidase family M48 family protein, anticorps zinc metallopeptidase, STE24, anticorps zinc metallopeptidase, STE24 homolog, anticorps ZMPSTE24, anticorps zmpste24.L, anticorps zmpste24, anticorps ATSTE24, anticorps Zmpste24

Sujet: ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.

Poids moléculaire: 55 kDa

ID gène: 10269

NCBI Accession: NP_005848

UniProt: O75844